Bring a large pot of salted water to a boil and cook the pasta according to the package directions until al dente. Drain thoroughly, then rinse under cold water until the pasta has cooled completely.
As the pasta cooks, prepare the vinaigrette. Add the extra-virgin olive oil, red wine vinegar, dried oregano, garlic powder, salt, and black pepper to a small bowl or jar. Whisk thoroughly, or seal and shake, until the dressing is fully emulsified.
Transfer the cooled pasta to a large serving bowl. Add the diced grilled chicken, Genoa salami, mozzarella pearls, halved cherry tomatoes, diced cucumber, thinly sliced red onion, and sliced black olives.
Drizzle the prepared vinaigrette evenly over the pasta mixture. Toss gently until all of the ingredients are thoroughly combined and coated with the dressing.
Cover the salad and refrigerate it for at least 30 minutes before serving so the flavors have time to blend. Serve chilled.